RESPONSE TO ELEXACAFTOR/TEZACAFTOR/IVACAFTOR IN PEOPLE WITH CYSTIC FIBROSIS WITH THE N1303K MUTATION: CASE REPORT AND REVIEW OF THE LITERATURE

Response to Elexacaftor/Tezacaftor/Ivacaftor in people with cystic fibrosis with the N1303K mutation: Case report and review of the literature

Cystic fibrosis (CF) is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) protein.Thousands of CFTR mutations have been identified, but only a fraction are known to cause CF, with the most common being the prototypical class II CFTR mutation F508del.Elexacaftor-Tezacaftor-Ivacaftor (ETI) is a CFTR modulator that

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Oligosecretory Myeloma With Amyloidosis and Alopecia

Amyloidosis is a systemic illness characterized by the extracellular deposition of abnormal proteins in body tissues and organs.In addition to renal involvement, amyloidosis can also present with a variety of skin manifestations, though rarely with alopecia.Sixteen cases of alopecia secondary to systemic amyloidosis are reported.There is one report

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Connectedness via Generalizations of Semi-Open Sets

We use the idea of the grill.This study generalized a new sort of linked space like -connected and -hyperconnected and investigated its features, as well as the relationship between it moen rothbury faucet and previously described notions.It also developed new sorts of functions, such as hyperconnected space, and identified their relationship by of

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